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I have a question about which file-sharing websites exist that are specifically designed for chemical file formats (e.g., .mol, .pdb, .sdf, .xyz, etc.). Would such a question be appropriate for this website or would it be labelled as off-topic or otherwise unsuitable for this SE?

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I think that's definitely a question of interest for the chemistry community. Databases (open or closed), amongst other online resources, are key in certains areas of chemistry, including crystallography, cheminformatics, etc.

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